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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
48.79
Human Site:
T222
Identified Species:
67.08
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
T342
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Dog
Lupus familis
XP_543550
1017
111618
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Rat
Rattus norvegicus
NP_001129232
1015
111665
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Frog
Xenopus laevis
Q8QFR2
1013
112021
T222
P
F
D
E
C
G
G
T
T
H
V
L
R
L
S
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
T222
P
F
S
E
C
G
G
T
T
H
V
L
R
L
S
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
T222
P
F
S
E
C
G
G
T
T
H
V
L
R
L
S
Fruit Fly
Dros. melanogaster
O17468
1047
113397
T220
P
F
E
E
C
G
G
T
T
H
I
L
R
L
S
Honey Bee
Apis mellifera
XP_001122939
838
91355
A71
C
Q
L
D
N
H
L
A
C
V
N
C
V
R
W
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
R168
N
A
R
K
L
P
D
R
I
T
V
L
N
D
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
S197
T
V
M
I
W
R
T
S
D
W
S
L
A
H
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
S208
H
W
A
K
S
L
G
S
T
F
F
R
R
L
G
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
C73
Q
D
L
Q
M
P
L
C
S
M
S
R
H
T
G
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
T222
V
N
N
F
I
L
E
T
S
I
S
V
P
F
K
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
93.3
86.6
0
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
93.3
100
6.6
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
26.6
0
6.6
P-Site Similarity:
N.A.
13.3
N.A.
46.6
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
0
0
0
6
0
0
0
0
6
0
0
% A
% Cys:
6
0
0
0
65
0
0
6
6
0
0
6
0
0
0
% C
% Asp:
0
6
48
6
0
0
6
0
6
0
0
0
0
6
0
% D
% Glu:
0
0
6
65
0
0
6
0
0
0
0
0
0
0
0
% E
% Phe:
0
65
0
6
0
0
0
0
0
6
6
0
0
6
0
% F
% Gly:
0
0
0
0
0
65
71
0
0
0
0
0
0
0
12
% G
% His:
6
0
0
0
0
6
0
0
0
65
0
0
6
6
0
% H
% Ile:
0
0
0
6
6
0
0
0
6
6
6
0
0
0
6
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
12
0
6
12
12
0
0
0
0
77
0
71
0
% L
% Met:
0
0
6
0
6
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
6
6
6
0
6
0
0
0
0
0
6
0
6
0
0
% N
% Pro:
65
0
0
0
0
12
0
0
0
0
0
0
6
0
0
% P
% Gln:
6
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
6
0
0
6
0
6
0
0
0
12
71
6
0
% R
% Ser:
0
0
12
0
6
0
0
12
12
0
18
0
0
0
65
% S
% Thr:
6
0
0
0
0
0
6
71
71
6
0
0
0
6
0
% T
% Val:
6
6
0
0
0
0
0
0
0
6
65
6
6
0
0
% V
% Trp:
0
6
0
0
6
0
0
0
0
6
0
0
0
0
6
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _